Sr. Bioinformatics Engineer

The Position

The Impact

• Design, build, and maintain scalable pipelines for processing and analyzing clinical grade 30x whole genome data.
• Support a wide range of genomic data types at consumer scale.
• Optimize performance, reliability, and cost of data processing pipelines across AWS and hybrid environments.
• Keep throughput high and latency predictable for end users.
• Develop production quality services and tools using Python, C#, SQL, and AWS, including Lambda, Glue, Batch, S3, and RDS.
• Power Sequencing's DNA apps and reports with the services and tools you build.
• Collaborate across product, science, engineering, and UX teams to translate scientific findings into clear, consumer friendly genetic insights that are easy to navigate.
• Establish and adhere to best practices for software engineering, data versioning, testing, observability, and documentation across bioinformatics workflows.
• Debug complex data and infrastructure issues with a systematic approach.
• Operate and improve production systems where correctness and reliability are critical.
• Leverage AI tools to increase productivity, code quality, and testing depth.
• Deliver high quality, validated output.

Dominant and Expressed Traits

• 5+ years of experience in bioinformatics, computational biology, computer science, or a related field.
• Strong hands on experience working with real world genomic datasets and file formats such as VCF, BAM, and FASTQ.
• Solid understanding of genomic databases, standards, and annotation resources.
• Proficient in Python, SQL, and C#, with a track record of writing clean, maintainable code.
• Designed and implemented bioinformatics pipelines and data processing systems in production.
• Built scalable, reliable systems on cloud platforms such as AWS, including the use of managed services.
• Familiar with containerization and orchestration technologies such as Docker and Kubernetes.
• Excellent problem solving skills and exceptional attention to detail.
• Fluent in English, both written and verbal, with clear communication across technical and non technical stakeholders.

Benefits Overview

• Comprehensive medical, dental, and vision insurance coverage
• 401(k) with company matching
• Paid time off (PTO)
• Paid volunteer time off
• Fully remote work with home office stipend
• Parental bonding leave
• Clinical-grade whole genome sequencing for you and your family (private and confidential)

Join Sequencing

• Redefine how people understand themselves through their DNA
• Build category-defining products alongside scientists, engineers, and innovators
• Contribute to technology that will improve and extend millions of lives
• Shape one of the most important emerging categories in AI and healthcare