Senior Research Scientist - Toxicology

<p>Each of us cares about someone who will need medicines. That’s why our vision is to repeatedly beat the odds to deliver breakthrough medicines to patients that need them. We pursue truth and scientific rigour and have the courage to work at the edge of the unknown.</p> <p>We are looking for a dynamic and detail-oriented Senior Research Scientist to join our growing Nonclinical Safety team. You will be responsible for supporting our team's efforts in developing and executing toxicology studies to assess the safety of our drug candidates. For this role, you will require a strong understanding of toxicology principles as well as hands-on experience with <em>in vitro </em>and/or <em>in vivo</em> studies.</p> <p><strong>How you might spend your days</strong></p> <ul> <li>Leading the design, planning, and oversight of <em>in vitro</em> safety and/or <em>in vivo</em> toxicology studies, ensuring alignment with global regulatory guidelines and strategic company objectives</li> <li>Serving as a subject matter expert (SME) for Nonclinical Safety within cross-functional project teams, actively representing the function in internal and external stakeholder meetings&nbsp;</li> <li>Providing critical assessment of complex toxicology data, translating and communicating clear, actionable risk-benefit evaluations and strategic recommendations to project teams and executive leadership</li> <li>Maintaining comprehensive and meticulous recording of nonclinical safety study data as required by Good Laboratory Practice (GLP)</li> <li>Authoring and critically reviewing the<em> in vitro</em> safety, toxicology, and safety pharmacology sections of Regulatory documentation (such as INDs, CTAs, IBs, and BLAs)&nbsp;</li> <li>Collaborating seamlessly with scientists across various matrixed teams at AbCellera to ensure high data quality and accelerate program advancement</li> <li>Contributing to the development of our toxicology programs and performing as a nonclinical safety/toxicology representative as needed</li> <li>Maintaining an active scan and synthesis of published toxicology literature and evolving regulatory guidance relevant to AbCellera’s product portfolio, translating insights into internal best practices&nbsp;</li> </ul> <p><strong>We'd love to hear from you if</strong></p> <ul> <li>You hold a PhD in Toxicology or a related field, and have a minimum of 5-8 years of related industry experience supporting biologics development; candidates with or a MSc and 10+ years of relevant experience will also be considered</li> <li>You have extensive hands-on experience with <em>in vitro</em> and/or <em>in vivo</em> toxicology studies</li> <li>You have demonstrated proficiency with nonclinical safety assessment of large molecules/ biologics</li> <li>You exhibit strong organizational, critical problem-solving, and analytical skills to assess complex datasets and propose strategic solutions&nbsp;</li> <li>You have excellent scientific writing, communication, and collaboration skills to effectively lead scientific discussions and influence decision-making</li> <li>You have DABT accreditation (highly desirable, but not required)</li> </ul> <p><strong>What we offer</strong></p> <p>AbCellera’s hiring range for this role is CAD $112,000 - $150,000 annually, commensurate with your education and job-related knowledge, skills, and experience. In addition to base salary, we offer equity, annual bonus dependent on team and company performance, and a 6% (non-match) RRSP contribution.&nbsp;</p> <p>You will have a CAD $1,500 annual Active Lifestyle Allowance, annual vacation, professional development opportunities, and comprehensive health benefits. Scientific and technical mentorship is a priority. And you’ll find a strong sense of community and connections across AbCellera through our work, clubs, and socials.</p> <p><strong>About AbCellera</strong></p> <p><strong><em>Creating medicines is the most important work we can do.&nbsp;</em></strong></p> <p>We are a clinical-stage biotechnology company focused on discovering and developing antibody-based medicines in the areas of endocrinology, women’s health, immunology, and oncology. We have built a platform for advancing antibody drug programs from target to clinic, and we are using it to build our internal pipeline. <br><br>Today, our pipeline includes two drug candidates in clinical development, two preclinical development candidates (DCs) in Investigational New Drug (IND)-enabling activities, and more than 20 active discovery programs across multiple modalities and indications.</p> <p>We believe that when tenacious people share a vision and work together, they can truly have a positive impact. That’s why we hire for character and intelligence, not just for CVs or experience.&nbsp;</p> <p>We look for people with drive and energy. People we trust. People who need to know their days are being well spent. That their work really matters. In the end, our success will be measured by the impact of our medicines.</p> <p><strong>To apply</strong></p> <p>Please submit your application through our website and refer to <strong>Job ID 23374</strong> in your cover letter. We receive a large volume of applications and are only able to contact those who are selected for an interview. All communication from our Talent Discovery team will come from an @abcellera.com email address.</p>