Principal Scientist, Biologics

About Boltz

About the role

About you

Essentials:

• PhD or equivalent, with additional industrial or academic research experience in biologics engineering, structural biology, protein science, bioengineering, or a closely related field.
• Strong hands-on experience designing, engineering, or characterizing biologics.
• Deep understanding of biologics discovery and optimization workflows.
• Ability to work closely with ML researchers and engineers, translating biological problems into clear modeling objectives and evaluation criteria.
• Experience interpreting computational model outputs and connecting them to biological and experimental outcomes.
• Product-minded scientific thinking, with the ability to influence platform design and roadmap decisions based on real user needs.
• Strong communication skills, able to articulate complex biological concepts to interdisciplinary teams.

Nice to have:

• Familiarity with structural modeling, docking, or protein design tools (e.g. structure prediction, scoring, or simulation workflows).
• Applied experience using Boltz models on biologic research projects.
• Interest in scaling scientific impact through platforms, tools, or open scientific infrastructure.

What we offer

• Opportunity to drive outsized real-world impact by building tools that empower thousands of scientists across the industry.
• Work alongside one of the most talent-dense teams in the field.
• Significant ownership and independence, with responsibility for driving projects from concept to deployment.
• Highly competitive salary with substantial equity ownership.